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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Length constant ： ウィキペディア英語版 Length constant In neurobiology, the length constant (λ) is a mathematical constant used to quantify the distance that a graded electric potential will travel along a neurite via passive electrical conduction. The greater the value of the length constant, the further the potential will travel. A large length constant can contribute to spatial summation—the electrical addition of one potential with potentials from adjacent areas of the cell. The length constant can be defined as: :$\backslash lambda\; \backslash \; =\; \backslash \; \backslash sqrt+\; r\_\}\}$ where rm is the membrane resistance (the force that impedes the flow of electric current from the outside of the membrane to the inside, and vice versa), ri is the axial resistance (the force that impedes current flow through the axoplasm, parallel to the membrane), and ro is the extracellular resistance (the force that impedes current flow through the extracellular fluid, parallel to the membrane). In calculation, the effects of ro are negligible, so the equation is typically expressed as: :$\backslash lambda\; \backslash \; =\; \backslash \; \backslash sqrt\; \}\}$ The membrane resistance is a function of the number of open ion channels, and the axial resistance is generally a function of the diameter of the axon. The greater the diameter of the axon, the lower the ri. The length constant is used to describe the rise of potential difference across the membrane :$V(x)\; \backslash \; =\; \backslash \; V\_\; (1\; -\; e^)$ The fall of voltage can be expressed as: :$V(x)\; \backslash \; =\; \backslash \; V\_\; (e^)$ Where voltage, V, is measured in millivolts, x is distance from the start of the potential (in millimeters), and λ is the length constant (in millimeters). Vmax is defined as the maximum voltage attained in the action potential, where: :$V\_\; \backslash \; =\; \backslash \; r\_I$ where rm is the resistance across the membrane and I is the current flow. Setting for x= λ for the rise of voltage sets V(x) equal to .63 Vmax. This means that the length constant is the distance at which 63% of Vmax has been reached during the rise of voltage. Setting for x= λ for the fall of voltage sets V(x) equal to .37 Vmax, meaning that the length constant is the distance at which 37% of Vmax has been reached during the fall of voltage. ==By resistivity== Expressed with resistivity rather than resistance, the constant λ is (with negligible ro):〔Page 202 in: 〕 :$\backslash lambda\; =\; \backslash sqrt\}\}$ Where $r$ is the radius of the neuron. The radius and number 2 come from that: *$\backslash rho\_\; =\; r\_\; \backslash times\; 2\backslash pi\; r$ *$\backslash rho\_\; =\; r\_\; \backslash times\; \backslash pi\; r^2$ Expressed in this way, it can be seen that the length constant increases with increasing radius of the neuron. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Length constant」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.